Oxygen, Innovation, and Healing: NATROX^® Wound Care is Actively Revolutionizing Chronic Wound Treatment

NATROX^® Wound Care is a pioneering medical technology company dedicated to transforming the management and outcomes of chronic wounds. Established from a single, profound commitment to improve the life of a loved one struggling with a non-healing wound, the organization’s driving force continues to be the enhancement of quality of life for patients with hard-to-heal wounds.Nancy Stahulak, VP Global Marketing and U.S. Sales at NATROX Wound Care recognizes the global impact of chronic wounds—a condition affecting millions and impeding daily living and well-being.

At the core of NATROX Wound Care’s product line is its flagship device, NATROX^® O₂ Continuous Topical Oxygen Therapy (cTOT). This innovative, wearable medical device delivers a consistent, low flow of highly concentrated oxygen directly to chronic wounds. Unlike more invasive or complicated wound treatment options, NATROX O₂ is non-invasive, lightweight, and portable, allowing patients to receive effective therapy around the clock, as they continue their activities of daily living. The simplicity and portability of the device make it suitable for use in multiple care settings, helping bridge the gap between advanced clinical technology and everyday practicality.

Strong clinical evidence supports the effectiveness of NATROX O₂ in treating diverse wound etiologies, including diabetic foot ulcers, venous leg ulcers, pressure injuries, and non-healing surgical wounds. The company has focused on ensuring that advanced wound healing is accessible to more patients by offering a scalable, user-friendly solution that does not add unnecessary complexity or financial burden to healthcare providers or patients.

NATROX Wound Care operates on a foundation of passion for medicine, compassion for patients,

respect among employees, and unwavering commitment to its customers. By putting patient-centered innovation at the forefront, the company enables healthcare professionals to achieve better clinical outcomes and restore hope for individuals who might otherwise face the severe consequences of untreated wounds. Through constant dedication and the application of leading-edge science, NATROX Wound Care aspires to redefine standards in wound care and help patients worldwide reclaim comfort, mobility, and quality of their lives.

Chronic Wound Healing With Oxygen

The science is compelling. Roughly 97% of chronic wounds are hypoxic—they lack enough oxygen to heal properly. While most advanced wound care products focus on moisture balance, exudate control, or infection management, very few directly address this oxygen deficit.

That’s the gap NATROX O₂ fills. By delivering a continuous, low-flow stream of highly concentrated oxygen straight to the wound bed, it enables healing at every stage of the process. And because it’s portable, patients don’t need to put their lives on pause to receive treatment.

The device comes with two rechargeable batteries—one in use while the other charges—and requires only one exchange per day. As healing progresses, dressing changes can become less frequent, many times as little as once a week. This reduces not just disruption of the patient’s day, but also dependency on clinic visits or caregivers. And that kind of independence matters.

Perhaps more compelling than the tech specs are the patient outcomes. In the NATROX O₂ pain study, 76% of patients reported substantial pain reduction. Over half became completely pain-free. On a 0-10 pain scale, average scores dropped from 8.2 to just 1.9. For anyone who has lived with the relentless discomfort of a chronic wound, that’s a profound transformation.

Economic Impact Meets Human Impact

The implications go far beyond individual recovery. Chronic wounds cost healthcare systems billions each year. The treatment process can stretch over six to eight months—or in some cases, much longer. Some patients live with open wounds for over a decade.

By accelerating healing, NATROX O₂ reduces the frequency of clinical visits, dressing changes, and the likelihood of complications. That translates into significant cost savings for providers, payers, and patients alike.

Durability is another major win. Recurrence is a common frustration in wound care, but 85% of patients using NATROX O₂ remained healed after one year. That kind of staying power changes the game.

There are other ripple effects too. Infections, which often derail the healing process, are less likely when continuous topical oxygen is in play, shown by emerging evidence that oxygen therapy helps manage antimicrobial resistance and biofilm, two stubborn challenges in modern wound care.

Even more sobering is the link between chronic wounds and amputation. It’s estimated that a limb is lost every 30 seconds due to complications from diabetic foot ulcers. Incorporating oxygen therapy like NATROX O₂ into standard care protocols has been shown to reduce amputation rates dramatically.

Then there’s the opioid angle. Chronic pain often leads to long-term opioid use, creating a dependency that can spiral into a separate crisis. With topical oxygen therapy, 69% of patients were able to stop using opioids altogether. That’s not just pain relief—it’s life-changing relief.

From Data to Global Endorsements

You can’t shift an industry on anecdotes alone. What’s pushed NATROX Wound Care into the international spotlight is its investment in robust clinical evidence. A randomized controlled trial published in the Journal of Wound Care showed that patients treated with NATROX O₂ had 71% higher healing rates and a 73% greater reduction in wound size than those in the control group. That study has since fueled inclusion in many meta-analyses and systematic reviews. It also played a role in topical oxygen therapy (TOT) earning recognition from organizations like the American Diabetes Association (which awarded TOT an “A grade”), the Wound Healing Society (WHS), and the International Working Group on the Diabetic Foot (IWGDF).

The company isn’t stopping at RCTs. It’s actively investing in post-market surveillance, economic modeling, and global registry initiatives to validate its long-term impact. These efforts open doors to better reimbursement models, broader access, and deeper adoption across public and private healthcare systems.

Education is another strategic pillar. NATROX Wound Care is equipping multidisciplinary teams—podiatrists, diabetes specialists, wound care specialists, and surgeons—with tools and evidence to make topical oxygen therapy a standard part for chronic and non-healing wound treatment.

Collaborating with Global Experts

To stay ahead of the curve, NATROX Wound Care isn’t working in a vacuum. The company collaborates with some of the most respected names in wound care, including Dr. Thomas Serena and Dr. Windy Cole. These clinicians have shaped and clinically supported the evolution of Continuous Topical Oxygen Therapy. Through advisory roles, research partnerships, and education initiatives, these global experts influence product development and clinical protocol design. They also serve as ambassadors at major conferences, spreading awareness of how topical oxygen therapy can transform chronic wound management. Their involvement ensures that the product is not only grounded in science but deeply aligned with clinical realities.

A MedTech Trailblazer with a Human Mission

NATROX Wound Care has twice topped the prestigious MedTech50 list, and for good reason. While many companies are racing to digitize or automate, NATROX Wound Care is focused on something more elemental—oxygen—and delivering it in a way that feels personal, practical, and powerful.

“We’re moving the conversation from care to heal,” says Nancy Stahulak. That shift in mindset permeates everything the company does.

Its product is transformative. Its evidence base is strong. Its mission is crystal clear: to eliminate the burden of non-healing wounds.

But what really sets NATROX Wound Care apart is its culture. It’s a company built on urgency, innovation, and empathy. It understands that healing isn’t just a clinical outcome—it’s about restoring comfort, mobility, and dignity.

NATROX Wound Care isn’t just a MedTech company. It’s a movement. One that’s reshaping expectations, one wound at a time.