Global Best Companies to Watch in 2025
“As healthcare evolves toward more consumer-driven models, with greater emphasis on access, equity, quality, and cost control, XiFin’s AI-enabled technology, data-driven analytics, and advanced services empower organizations to navigate these shifts and thrive.”
The Silicon Review
XiFin Empower RCM Delivers Improved Financial Performance
XiFin is a healthcare technology company focused on solving the revenue cycle management (RCM) challenges facing diagnostic providers, hospitals, pharmacies, and outpatient service providers. With headquarters in San Diego, California, XiFin serves a national client base that includes many of the largest and most respected healthcare organizations in the United States. Its solutions are used by 11 of the 15 largest public laboratories, four of the five leading integrated delivery networks (IDNs), and the top five retail pharmacy chains.
At the core of XiFin’s offerings is XiFin Empower RCM, a cloud-based, AI-enabled revenue cycle management platform designed to improve financial performance, reduce administrative burden, and increase operational efficiency. Built on a secure, cloud-native infrastructure, the platform uses artificial intelligence (AI) and machine learning to automate key revenue cycle tasks such as claim submission, denial management, and documentation processing. This reduces manual intervention, minimizes errors, and accelerates reimbursement. Designed for scalability and security, its open API framework allows for bi-directional data exchanges. Additionally, XiFin offers a range of flexible RCM medical billing services that give organizations the option to delegate portions or all of their billing operations, based on their operational needs. This hybrid model helps providers to free internal resources and scale while maintaining operational control.
XiFin’s approach combines technological innovation with deep industry expertise and tailored service models. Real-time analytics offer actionable insights that help organizations identify reimbursement trends, optimize workflows and resource allocations, and make informed financial and operational decisions.
In conversation with Kyle Fetter, COO of XiFin
XiFin’s tagline is “The Power to Do Good.” How does this long-term mission influence your innovation roadmap and client partnerships globally?
“The Power to Do Good” isn’t just a tagline for XiFin, it’s a guiding philosophy that informs every aspect of the company’s mission. As a leader in SaaS-based RCM and workflow automation solutions, XiFin helps healthcare providers to optimize revenue cycles, navigate the challenging regulatory environment, and manage industry change. We empower providers to achieve financial strength, so they can do more good for more patients. We support this philosophy with a deep commitment to three pillars:
Innovation: XiFin leads the industry in building tightly integrated, secure, reliable, and scalable healthcare technology platforms that improve financial performance. We empower our clients with innovative solutions for revenue cycle management, laboratory information systems, pharmacy clinical documentation and patient engagement, and medical billing services.
Expertise: We bring business, operational, and clinical value across a spectrum of applications and use cases, backed by decades of experience in healthcare financial management, technology, and analytics. Our knowledge and insights are part of why our clients consider us a trusted partner.
Advocacy: XiFin actively engages across the healthcare ecosystem, including regulators, lawmakers, industry associations, and payors. By working with stakeholders, we champion thoughtful modernization of healthcare so that providers can ensure continued innovation, improved care, and a healthcare system that works better for everyone.
What makes XiFin Empower a game-changer in the global healthcare revenue cycle management space?
XiFin Empower RCM is a powerful healthcare technology infrastructure that unifies the best of automation, data analytics, and artificial intelligence (AI) to facilitate end-to-end connectivity and workflow optimization from the initial patient encounter to a zero-balance bill. The Empower platform offers real-time data exchange and supports interoperability between systems and data sources, connecting providers, payors, and patients to get the information they need when they need it, ultimately streamlining operations, achieving stronger finances, and enhancing the patient/provider experience.
Consistently ranked #1 by Black Book Market Research, Empower RCM is the trusted choice for healthcare providers. Its advanced, AI-driven automation streamlines workflows, reduces denials, accelerates reimbursements, and ensures compliance—helping providers achieve financial stability and operational excellence. Our HITRUST® r2 certification further underscores our commitment to the highest standards of security and compliance.
XiFin Empower RCM drives measurable improvements for its clients, including a 97% or better first-pass claim acceptance rate, and up to a 50% reduction in denials. Providers typically experience an average 10% or greater increase in collections and a far better physician/patient experience, contributing to billions of dollars in net cash collection gains across XiFin’s client base.
As healthcare evolves toward more consumer-driven models, with greater emphasis on access, equity, quality, and cost control, XiFin’s AI-enabled technology, data-driven analytics, and advanced services empower organizations to navigate these shifts and thrive.
With value-based care gaining momentum worldwide, how is XiFin positioning itself as a strategic enabler for healthcare organizations navigating this global shift?
XiFin Empower RCM helps healthcare providers to navigate the evolving healthcare landscape and supports key components of value-based care, including:
Improved RCM: Value-based care requires organizations to achieve financial strength and efficiency in order to focus on providing high-quality care and improving patient outcomes. Empower RCM helps maximize reimbursements, optimize billing and accounts receivable processes, and streamline workflows.
Enhanced Patient and Client Engagement: Successful value-based care initiatives require active participation from both patients and referring physicians. XiFin’s patient and provider portals improve engagement by enabling patients to access and update account information, view statements, and make payments, and allowing referring physicians to enter orders, review statements, and access testing information.
Actionable Insights and Analytics: Value-based care relies heavily on data-driven decision-making. XiFin provides solutions with robust advanced analytics capabilities that offer actionable “insights into key metrics, like gaps in care, patient outcomes, and cost-efficiency.”
Compliance and Regulatory Support: Navigating regulations and payor policies is important in a value-based care environment. Empower RCM is designed to support compliance and incorporate payor edits and requirements, minimizing the risk of fraud, waste, and abuse. XiFin also actively engages with regulators and payors to advocate for policies that reduce administrative burdens and support fair and stable reimbursement.
Interoperability and Data Exchange: A critical component of value-based care is the ability to share information seamlessly among different healthcare providers and systems. XiFin’s technology infrastructure facilitates the exchange and management of key healthcare data, reports, and images, enabling end-to-end connectivity and streamlined workflow across the healthcare ecosystem.
XiFin plays a critical role in helping value-based companies succeed by providing the technology and services necessary to optimize their revenue cycle, improve patient and provider engagement, leverage data for actionable insights, ensure compliance, facilitate data exchange, and support the broader goals of delivering high-quality, cost-effective care.
What does the future hold for your company and its customers? Are exciting things on the way?
Looking ahead, XiFin recognizes the critical role of technology in advancing interoperability and remains deeply committed to improving connectivity and efficiency across the healthcare ecosystem. Innovations such as artificial intelligence and predictive analytics will continue to drive greater automation, smarter decision-making, and enhanced operational performance.
As U.S. healthcare contends with regulatory upheaval, rising costs, clinician shortages, and the growing burden of chronic disease, we are seeing transformative shifts across the ecosystem. Pharmacists, for example, are stepping into a larger role as essential care providers.
At the same time, innovative medical devices are enabling more precise diagnosis and continuous monitoring of health conditions, supporting a more proactive approach to care. The shift toward a consumer-driven healthcare model is further amplifying the need for seamless, coordinated patient information across a fragmented provider landscape. And as hospitals and health systems rethink their care delivery models, they are also working to better integrate and optimize financial operations for ancillary services, not just traditional inpatient care.
Additionally, pharmacies and medical device companies are increasingly navigating within complex medical billing environments that are new to them — a trend that underscores the importance of flexible, intelligent revenue cycle management solutions.
No matter how healthcare evolves, XiFin’s mission remains constant: to empower healthcare organizations to operate more efficiently, achieve financial strength, and enable them to do more good for more patients.