× Business
TelecomHealthcareDigital MarketingERPRetailMedia and EntertainmentOil and GasFood and BeveragesMarketing and AdvertisingBanking and Insurance
Technology
Big DataCloudIT ServiceSoftwareMobileSecurityNetworkingStorageCyber SecuritySAPData AnalysisloTBio Tech
Platform
Cisco DATABASE Google IBM Juniper Microsoft M2M Oracle Red hat Saas SYMANTEC
Leadership
CEO ReviewCMO ReviewCFO ReviewCompany Review
Magazines
US INDIA ASIA ARCHIVE
Startups Opinion Yearbook Readers Speak Contact Us

Bacteria can now be used to make natural colors from simple sugar

siliconreview Bacteria can now be used to make natural colors from simple sugar

Researchers at Rensselaer Polytechnic Institute have shown that four strains of E. coli bacteria working together can convert sugar into the natural red anthocyanin pigment found in strawberries, opening the door to economical natural colors for industrial applications. “The research marks the first biosynthesis method using four strains of bacteria to manufacture a compound in a single step”, said Mattheos Koffas, a professor of chemical and biological engineering at Rensselaer. “We feed the bacteria glucose and they do the rest”, he added.

Koffas’ lab has been investigating a production method of anthocyanins involving genetic engineering since 2005. In its current research, the molecular pathway was divided into modules among four different strains of bacteria and modified to assemble anthocyanin in stages. The modules produced intermediates that easily diffuse out of the bacterial cell. When combined in a single flask, the first bacteria ingest sugar and produce "intermediate" compounds, phenylpropanoic acids, which are then ingested by the second bacteria. This produces a second intermediate and this continues until the fourth strain produces anthocyanin.

In the next stage, researchers optimized each stage of the process. Each of the four strains was chosen based on its ability to produce its assigned intermediate. Some segments produced more than others, and the final output produced few milligrams per liter of anthocyanin. "I have no doubt that production of anthocyanins from a recombinant microbial host is the only viable method for making these compounds in an economically sustainable manner," said Koffas.

YOU MIGHT ALSO LIKE::

ENROLL FOR UPCOMING ISSUE